Are you treating peripheral artery disease (PAD) in the infrapopliteal or femoropopliteal regions? We are excited to introduce our Advance Serenity 0.018 inch diameter and Advance Serenity 0.014 inch diameter balloon dilatation catheters. Whether targeting the infrapopliteal or femoropopliteal arteries, this next-generation technology provides a smoother crossing of tight lesions.
Watch these videos:
Dr Anahita Dua discusses her PAD practice.
Dr Keith Jones talks about using Advance Serenity.
How does Advance Serenity fit into your PAD algorithm?
I use [Advance] Serenity balloons for below-the-knee pathology where trackability is essential to reach those tough lesions.
What type of lesion is Advance Serenity best suited for?
Any lesion that is exceptionally tight or calcified is appropriate for this balloon, as I have almost always been able to track a[n] [Advance] Serenity balloon to the location I need to because of the way the tip travels.
How does the laser-formed tip aid in trackability?
I think this is the ticket to why the balloon glides so well and can reach very difficult locations that are tough to traverse with conventional balloons.
What are the particular PAD disease states that Advance Serenity best treats?
I have been using the [Advance] Serenity balloon for our patients with tibial disease. In many patients with diabetes and end-stage renal disease (ESRD), you may not see the typical femoropopliteal distribution of occlusive PAD that had traditionally been treated with bypass surgery. Often in these patients, you lose your outflow vessels first, which speaks to the importance of avoiding injury to the tibial arteries as there often is no open surgical option if endovascular techniques fail. [Advance] Serenity, in my experience, has been particularly helpful in this arterial bed.
How does the laser-formed tip help create a smooth transition to cross complex lesions?
This is a question I have a hard time answering since I have not considered the mechanisms of the balloon because it rarely fails. It is not just a matter of ability to cross, but also minimising trauma to the lumen when crossing, particularly in tibial arteries where there are few technical solutions to dissection or perforation. Although these may not be devastating complications, when the only vessel you can improve upon is affected, this undoubtedly can lead to a worse outcome for the patient.
Dr Anahita Dua is a paid consultant of Cook Medical.
Explore how the Advance Serenity® 18 Hydrophilic PTA Balloon Dilation Catheter:
See the Advance Serenity 18 versus other PTA Balloon Catheters graph featured in this product animation.
The Advance Serenity 18 Hydrophilic PTA Balloon Dilatation Catheter is indicated for the percutaneous transluminal angioplasty (PTA) dilation of peripheral vasculature stenosis in the iliac, femoral, popliteal, infrapopliteal, and renal arteries, and for the treatment of obstructive lesions of native or synthetic arteriovenous dialysis fistulas.
The Advance Serenity balloon was evaluated for crossability against leading competitors by measuring the average force (in grams) needed to traverse a synthetic lesion within an anatomical model.
Compared to leading competitors, the Advance Serenity 18 has proven to have excellent crossability using minimal force. With its laser-formed tip design and next-generation hydrophilic coating, the Advance Serenity 18 demonstrated superior crossability within a synthetic lesion. Coaxial shaft design balances stiffness and flexibility to deliver pushability to cross distal lesions. Its pleated balloon design and broad range of diameters enable you to treat the entire limb and may help save time.
| Catheter platform | Over the wire (OTW) |
|---|---|
| Recommended wire guide diameter | 0.018 inch |
| Sheath compatibility | 4, 4.5, 5, 5.5 Fr |
| Catheter working length | 90 cm and 135 cm (all sizes) |
| Balloon diameters | 5-10 mm |
| Balloon lengths | 20-150 mm |
| Nominal pressure | 8 atm (all sizes) |
| Rated burst pressure | 10-16 atm |
| Catheter platform | Over the wire (OTW) |
|---|---|
| Recommended wire guide diameter | 0.018 inch |
| Sheath compatibility | 4 Fr (all sizes) |
| Catheter working length | 150 cm (all sizes) |
| Balloon diameters | 2-4 mm (0.5 mm increments) |
| Balloon lengths | 20-220 mm |
| Nominal pressure | 8 atm (all sizes) |
| Rated burst pressure | 16 atm (all sizes) |
The Advance Serenity 14 Hydrophilic PTA Balloon Dilatation Catheter is indicated for percutaneous transluminal angioplasty (PTA) dilation of peripheral vasculature stenosis in the iliac, femoral, iliofemoral, popliteal, infrapopliteal, and renal arteries, and for the treatment of obstructive lesions of native or synthetic arteriovenous dialysis fistulas.
• All of the balloon sizes are compatible with 4 Fr sheaths.
• Balloon lengths of up to 220 mm allow for the treatment of longer lesions with fewer inflations and deflations.
The Advance Serenity balloon was evaluated for crossability against leading competitors by measuring the average force (in grams) needed to traverse a synthetic lesion within an anatomical model.
Compared to leading competitors, the Advance Serenity 14 has proven to have excellent crossability using minimal force. With its laser-formed tip design and next-generation hydrophilic coating, the Advance Serenity 14 demonstrated superior crossability within a synthetic lesion. Coaxial shaft design balances stiffness and flexibility to deliver pushability to cross distal lesions. Its pleated balloon design and broad range of diameters enable you to treat the entire limb and may help save time.
| Catheter platform | Over the wire (OTW) |
|---|---|
| Recommended wire guide diameter | 0.014 inch |
| Sheath compatibility | 4 Fr (all sizes) |
| Catheter working length | 120-150 cm (all sizes) |
| Balloon diameters | 2-4 mm (0.5 mm increments) |
| Balloon lengths | 20-220 mm |
| Nominal pressure | 6 atm (all sizes) |
| Rated burst pressure | 16 atm (all sizes) |
Please click the button below and submit the required information to connect with your local Cook representative. This form is intended for European-based physicians only.
Advance Serenity® 14 Brochure
Advance Serenity® 18 Brochure
The product information on this website is intended only for physicians and healthcare professionals licensed in the European Union (except France), the United Kingdom, Switzerland, Norway, Iceland, Turkey, and Liechtenstein.
If your region is not listed, visit our Ordering & Returns for more information.
Information provided on this site is not intended to be professional medical advice. Product Instructions for Use (IFU) should be consulted before use of any product.
PI-WF508000-EN
The product information on this website is intended only for physicians and healthcare professionals licensed in the European Union (except France), the United Kingdom, Switzerland, Norway, Iceland, Turkey, and Liechtenstein. If you are located in another global region, please click on the regional flag at the very top of the webpage and choose your region from the drop-down options.
If your region is not listed, visit our How to Order section for more information.
Information provided on this site is not intended to be professional medical advice. Product Instructions for Use (IFU) should be consulted before use of any product.